Pharmacokinetics and homeostatic impact of golden bile powder: evidence from surrogate analyte-based UPLC-MS/MS in rats

Abstract Background Golden bile powder (GBP), an artificial bear bile powder, is used for liver protection and contains taurine-conjugated bile acids (BAs) with broad pharmacological activities. However, its pharmacokinetics and effects on endogenous BA homeostasis are unclear. Methods Sprague–Dawle...

Descrición completa

Detalles Bibliográficos

Principais autores:	Xin Yu, Siyang Wu, Huinan Wang, Zheng Yuan, Lifeng Zhao, Xuehao Cheng, Zhishan Huang, Qiutao Wang, Qing Zhu, Luyang Liu, Chen Kang, Baolin Bian, Yingfei Li
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-04-01
Series:	Chinese Medicine
Assuntos:	Bile acids Golden bile powder Pharmacokinetics Surrogate analyte Endogenous bile acids Exogenous bile acids
Acceso en liña:	https://doi.org/10.1186/s13020-026-01371-7
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!