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New insights into Wnt - Lrp5/6 - β-catenin signaling in mechanotransduction

Mechanical loading is essential to maintain normal bone metabolism and the balance between bone formation and resorption. The cellular mechanisms that control mechanotransduction are not fully defined, but several key pathways have been identified. We discuss the roles of several components of the...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Alexander eRobling, Kyung Shin eKang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015-01-01
Schriftenreihe:Frontiers in Endocrinology
Schlagworte:
Online-Zugang:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00246/full
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