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Inactivated rabies-based Lassa fever virus vaccine candidate LASSARAB protects nonhuman primates from lethal disease

Abstract Lassa fever virus (LASV), a member of the Arenavirus family, is the etiological agent of Lassa fever, a severe hemorrhagic disease that causes considerable morbidity and mortality in the endemic areas of West Africa. LASV is a rodent-borne CDC Tier One biological threat agent and is on the...

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Principais autores: Gabrielle Scher, Catherine Yankowski, Drishya Kurup, Nicole M. Josleyn, Eric R. Wilkinson, Jay Wells, Jesse Steffens, Ginger Lynn, Sean Vantongeren, Xiankun Zeng, Nancy Twenhafel, Kathleen A. Cashman, Matthias J. Schnell
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-08-01
Serier:npj Vaccines
Online adgang:https://doi.org/10.1038/s41541-024-00930-z
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