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Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE

Abstract Background RNA is a critical analyte for unambiguous detection of actionable mutations used to guide treatment decisions in oncology. Currently available methods for gene fusion detection include molecular or antibody-based assays, which suffer from either being limited to single-gene targe...

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Principais autores: Eleanor R Gray, Justyna M Mordaka, Efthimia R Christoforou, Kristine von Bargen, Nicola D Potts, Christina Xyrafaki, Ana-Luisa Silva, Magdalena Stolarek-Januszkiewicz, Katarzyna Anton, Paulina K Powalowska, Simonetta Andreazza, Alessandro Tomassini, Rebecca N Palmer, Aishling Cooke, Robert J Osborne, Barnaby W Balmforth
格式: Artigo
語言:Inglês
出版: BMC 2022-10-01
叢編:BMC Medical Genomics
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在線閱讀:https://doi.org/10.1186/s12920-022-01363-0
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