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Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis.

Mycobacterium tuberculosis is an intracellular pathogen of macrophages and escapes the macrophages' bactericidal effectors by interfering with phagosome-lysosome fusion. IFN-γ activation renders the macrophages capable of killing intracellular mycobacteria by overcoming the phagosome maturation bloc...

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Váldodahkkit: Susanne Herbst, Ulrich E Schaible, Bianca E Schneider
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2011-05-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3085516?pdf=render
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