Effect of BAFF blockade on the B cell receptor repertoire and transcriptome in a mouse model of systemic lupus erythematosus

IntroductionSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. Anti-B-cell-activating factor (BAFF) therapy effectively depletes B cells and reduces SLE disease activity. This research aimed to evaluate the effect of BAFF blockade on B cell receptor (BCR) repertoire and gene e...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Tao Huang, Chenyu Pi, Xiaoqing Xu, Yan Feng, Jingming Zhang, Hua Gu, Jianmin Fang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-01-01
Edice:	Frontiers in Immunology
Témata:	systemic lupus erythematosus B cell receptor (BCR) repertoire transcriptome B cell-activating factor (BAFF) MRL/lpr
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1307392/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!