Effects and mechanisms of 6-hydroxykaempferol 3,6-di-O-glucoside-7-O-glucuronide from Safflower on endothelial injury in vitro and on thrombosis in vivo

Background: The florets of Carthamus tinctorius L. (Safflower) is an important traditional medicine for promoting blood circulation and removing blood stasis. However, its bioactive compounds and mechanism of action need further clarification.Objective: This study aims to investigate the effect and...

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Principais autores:	Li-Wei Wang, Jiang-Feng He, Hai-Yan Xu, Peng-Fei Zhao, Jie Zhao, Cong-Cong Zhuang, Jian-Nan Ma, Chao-Mei Ma, Yong-Bin Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-09-01
coleção:	Frontiers in Pharmacology
Assuntos:	Carthamus tinctorius 6-hydroxykaempferol 3,6-di-O-glucoside-7-O-glucuronide (HGG) human umbilical vein endothelial cells (HUVECs) oxygen glucose deprivation/reoxygenation (OGD/R) phenylhydrazine (PHZ) anti-thrombosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2022.974216/full
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