An isofagomine analogue with an amidine group in the 1,6-position
The synthesis of an isofagomine analogue with an amidine group in the 1,6-position is described. Density functional theory calculations showed that this compound has a remarkably different charge distribution compared with isofagomine. This may explain why the amidine is a poor glycosidase inhibitor...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2025-02-01
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| Schriftenreihe: | Royal Society Open Science |
| Schlagworte: | |
| Online-Zugang: | https://royalsocietypublishing.org/doi/10.1098/rsos.241877 |
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