The 19-bp deletion polymorphism of dihydrofolate reductase (DHFR) and nonsyndromic cleft lip with or without cleft palate: evidence for a protective role

Objective Nonsyndromic cleft lip with or without cleft palate (NS-CL/P) are among the most common congenital birth defects worldwide. Several lines of evidence point to the involvement of folate, as well as folate metabolizing enzymes in risk reduction of orofacial clefts. Dihydrofolate reductase (D...

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Principais autores:	Firoozeh RAFIGHDOOST, Amir RAFIGHDOOST, Houshang RAFIGHDOOST, Mohammad-Ayoob RIGI-LADEZ, Mohammad HASHEMI, Ebrahim ESKANDARI-NASAB
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Faculdade De Odontologia De Bauru - USP 2015-06-01
Colecção:	Journal of Applied Oral Science
Assuntos:	Dihydrofolate reductase (DHFR) Nonsyndromic cleft lip with or without cleft palate (NS-CL/P) Ins/Del polymorphism
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572015000300272&lng=en&tlng=en
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