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Pharmacokinetic–Pharmacodynamic Modeling of Midazolam in Pediatric Surgery

Midazolam (MDZ) is used for sedation in surgical procedures; its clinical effect is related to its receptor affinity and the dose administered. Therefore, a pharmacokinetic–pharmacodynamic (PK-PD) population model of MDZ in pediatric patients undergoing minor surgery is proposed. A descriptive, obse...

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Principais autores: Carmen Flores-Pérez, Luis Alfonso Moreno-Rocha, Juan Luis Chávez-Pacheco, Norma Angélica Noguez-Méndez, Janett Flores-Pérez, Delfina Ortiz-Marmolejo, Lina Andrea Sarmiento-Argüello
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-11-01
Serier:Pharmaceutics
Fag:
midazolam
PK-PD population model
sedation
pediatrics
minor surgeries
Online adgang:https://www.mdpi.com/1999-4923/15/11/2565
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