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Monitoring monocyte HLA-DR expression and CD4 + T lymphocyte count in dexamethasone-treated severe COVID-19 patients

Abstract Background A 10-day dexamethasone regimen has emerged as the internationally adopted standard-of-care for severe COVID-19 patients. However, the immune response triggered by SARS-CoV-2 infection remains a complex and dynamic phenomenon, leading to various immune profiles and trajectories. T...

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Autori principali: Guillaume Monneret, Nicolas Voirin, Jean-Christophe Richard, Martin Cour, Thomas Rimmelé, Lorna Garnier, Hodane Yonis, Remy Coudereau, Morgane Gossez, Christophe Malcus, Florent Wallet, Marie-Charlotte Delignette, Frederic Dailler, Marielle Buisson, Laurent Argaud, Anne-Claire Lukaszewicz, Fabienne Venet, for the RICO study group
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-05-01
Serie:Annals of Intensive Care
Soggetti:
Immunomonitoring
Monocyte
HLA-DR
CD4
COVID-19
Dexamethasone
Accesso online:https://doi.org/10.1186/s13613-024-01310-5
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