Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models

Falcarindiol (FaDOH) is a cytotoxic and anti-inflammatory polyacetylenic oxylipin found in food plants of the carrot family (Apiaceae). FaDOH has been shown to activate PPARγ and to increase the expression of the cholesterol transporter ABCA1 in cells, both of which play an important role in lipid m...

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Principais autores:	Camilla Bertel Andersen, Anders Runge Walther, Emma Pipó-Ollé, Martine K. Notabi, Sebastian Juul, Mathias Hessellund Eriksen, Adam Leslie Lovatt, Richard Cowie, Jes Linnet, Morten Kobaek-Larsen, Rime El-Houri, Morten Østergaard Andersen, Martin Aage Barsøe Hedegaard, Lars Porskjær Christensen, Eva Christensen Arnspang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-08-01
coleção:	Frontiers in Pharmacology
Assuntos:	falcarindiol lipid droplets cholesteryl esters PPARγ ABCA1 colorectal cancer
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2020.565524/full
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