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In Vitro Analyses of the Toxicity, Immunological, and Gene Expression Effects of Cobalt-Chromium Alloy Wear Debris and Co Ions Derived from Metal-on-Metal Hip Implants

Joint replacement has proven to be an extremely successful and cost-effective means of relieving arthritic pain and improving quality of life for recipients. Wear debris-induced osteolysis is, however, a major limitation and causes orthopaedic implant aseptic loosening, and various cell types inclu...

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Principais autores: Olga M. Posada, Rothwelle J. Tate, R.M. Dominic Meek, M. Helen Grant
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-07-01
coleção:Lubricants
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Acesso em linha:http://www.mdpi.com/2075-4442/3/3/539
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