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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib Induces Dry Skin via Decreased in Aquaporin-3 Expression

An adverse reaction of dry skin occurs frequently during treatment with anticancer epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). In this study, we conducted basic research to clarify the mechanism of EGFR-TKI-induced dry skin and propose new treatments or preventative meas...

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Principais autores: Nobutomo Ikarashi, Miho Kaneko, Tomofumi Watanabe, Risako Kon, Makana Yoshino, Takatoshi Yokoyama, Riho Tanaka, Naoya Takayama, Hiroyasu Sakai, Junzo Kamei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-04-01
coleção:Biomolecules
Assuntos:
aquaporin-3
dry skin
erlotinib
EGFR
ERK
Acesso em linha:https://www.mdpi.com/2218-273X/10/4/545
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