Feasibility and Efficacy of Adjuvant Chemotherapy With Gemcitabine After Liver Transplantation for Perihilar Cholangiocarcinoma - A Multi-Center, Randomized, Controlled Trial (pro-duct001)

BackgroundLiver transplantation (LT) is considered a therapeutic option for unresectable perihilar cholangiocarcinoma (PHC) within defined criteria. It remains uncertain whether patients can safely receive adjuvant chemotherapy after LT.MethodsWe performed a prospective, multi-center, randomized, no...

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Autori principali:	Moritz Schmelzle, Christian Benzing, Lutz Fischer, Uta Herden, Martina Sterneck, Utz Settmacher, Astrid Bauschke, Ulf Neumann, Uwe Pelzer, Tobias Müller, Christian Strassburg, Hauke Lang, Thomas Becker, Alfred Königsrainer, Silvio Nadalin, Markus Quante, Andreas Paul, Helmut Friess, Jürgen Klempnauer, Nicolas Richter, Florian Vondran, Andreas Pascher, Thomas Rösch, Wenzel Schöning, Felix Krenzien, Robert Öllinger, Daniel Seehofer, Peter Neuhaus, Johann Pratschke
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-10-01
Serie:	Frontiers in Oncology
Soggetti:	perihilar and intrahepatic cholangiocarcinoma klatskin tumor adjuvant chemotherapy gemcitabine liver transplantation proximal bile duct cancer
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2022.910871/full
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