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A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentation

Abstract Background Male infertility is a global health issue. The more causative genes related to human male infertility should be further explored. The essential role of Zcwpw1 in male mouse fertility has been established and the role of ZCWPW1 in human reproduction needs further investigation to...

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Hauptverfasser: Yuelin Song, Juncen Guo, Yanling Zhou, Xingjian Wei, Jianlan Li, Guohui Zhang, Hongjing Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-02-01
Schriftenreihe:Reproductive Health
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Online-Zugang:https://doi.org/10.1186/s12978-024-01746-9
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