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Rapid induction and long-term self-renewal of neural crest-derived ectodermal chondrogenic cells from hPSCs

Abstract Articular cartilage is highly specific and has limited capacity for regeneration if damaged. Human pluripotent stem cells (hPSCs) have the potential to generate any cell type in the body. Here, we report the dual-phase induction of ectodermal chondrogenic cells (ECCs) from hPSCs through the...

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Huvudupphov: Pei Shen, Lu Chen, Dahe Zhang, Simo Xia, Zhuman Lv, Duohong Zou, Zhiyuan Zhang, Chi Yang, Wenlin Li
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2022-12-01
Serie:npj Regenerative Medicine
Länkar:https://doi.org/10.1038/s41536-022-00265-0
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