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Case Report: Durable response to PD-1 blockade after failure of ALK-targeted therapy and chemoimmunotherapy in ALK-positive large B-cell lymphoma

BackgroundAnaplastic lymphoma kinase–positive large B-cell lymphoma (ALK+ LBCL) is an exceedingly rare and aggressive subtype of B-cell non-Hodgkin lymphoma, comprising less than 1% of all LBCL cases. These tumors often exhibit resistance to standard chemoimmunotherapy and targeted approaches, resul...

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Detaylı Bibliyografya
Asıl Yazarlar: Guilherme Gasparini Spiandorelo, Ahmed Alnughmush, Olivia Crum, Dragan Jevremovic, J. C. Villasboas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2026-01-01
Seri Bilgileri:Frontiers in Hematology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/frhem.2025.1683981/full
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