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White matter microstructural and macrostructural profiles during midlife reveal sex differences between men and women at different menopausal stages

Abstract Women are at greater lifetime risk for Alzheimer’s disease (AD), potentially due to midlife endocrine transition effects on bioenergetics and gray and white matter volumes. Key to effective neurotransmission is white matter integrity. In this cross-sectional diffusion-weighted imaging analy...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Adam C. Raikes, Jonathan P. Dyke, Matilde Nerattini, Camila Boneu, Trisha Ajila, Francesca Fauci, Michael Battista, Silky Pahlajani, Schantel Williams, Roberta Diaz Brinton, Lisa Mosconi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-11-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-025-24136-y
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