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Bioreactor-Grown Bacillus of Calmette and Guérin (BCG) Vaccine Protects Badgers against Virulent <i>Mycobacterium bovis</i> When Administered Orally: Identifying Limitations in Baited Vaccine Delivery

Bovine tuberculosis (TB) in Great Britain adversely affects animal health and welfare and is a cause of considerable economic loss. The situation is exacerbated by European badgers (<i>Meles meles</i>) acting as a wildlife source of recurrent <i>Mycobacterium bovis</i> infection to cattle. Vaccinati...

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Autors principals: Sandrine Lesellier, Colin P. D. Birch, Dipesh Davé, Deanna Dalley, Sonya Gowtage, Simonette Palmer, Claire McKenna, Gareth A. Williams, Roland Ashford, Ute Weyer, Sarah Beatham, Julia Coats, Alex Nunez, Pedro Sanchez-Cordon, John Spiropoulos, Stephen Powell, Jason Sawyer, Jordan Pascoe, Charlotte Hendon-Dunn, Joanna Bacon, Mark A. Chambers
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-08-01
Col·lecció:Pharmaceutics
Matèries:
BCG
oral vaccine
tuberculosis
badgers
bait
fermentation
Accés en línia:https://www.mdpi.com/1999-4923/12/8/782
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