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The Relationship between Gray Matter Quantitative MRI and Disability in Secondary Progressive Multiple Sclerosis.

In secondary progressive Multiple Sclerosis (SPMS), global neurodegeneration as a driver of disability gains importance in comparison to focal inflammatory processes. However, clinical MRI does not visualize changes of tissue composition outside MS lesions. This quantitative MRI (qMRI) study investi...

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Principais autores: René-Maxime Gracien, Alina Jurcoane, Marlies Wagner, Sarah C Reitz, Christoph Mayer, Steffen Volz, Stephanie-Michelle Hof, Vinzenz Fleischer, Amgad Droby, Helmuth Steinmetz, Frauke Zipp, Elke Hattingen, Ralf Deichmann, Johannes C Klein
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4981438?pdf=render
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