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Pd-catalyzed enantioselective intramolecular Heck reaction to access disubstituted dihydroisoquinolinone with a terminal olefin

A first palladium-catalyzed asymmetric intramolecular Heck reaction for the construction 3,4-dihydro-1-(2H)-isoquinolinone containing the quaternary carbon chiral center has been developed. The salient features of this reaction include high efficiency, high enantioselectivity, the novel chiral ligan...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Sanliang Li, Qiaoyu Chen, Zhan-Ming Zhang, Junliang Zhang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: KeAi Communications Co. Ltd. 2021-11-01
Rangatū:Green Synthesis and Catalysis
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Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2666554921000879
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