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The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity

Neutrophils express the two formyl peptide receptors (FPR1 and FPR2) and the medium-chain fatty acid receptor GPR84. The FPRs are known to define a hierarchy among neutrophil G protein-coupled receptors (GPCRs), that is, the activated FPRs can either suppress or amplify GPCR responses. In this study...

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Principais autores: Jonas Mårtensson, Martina Sundqvist, Asmita Manandhar, Loukas Ieremias, Linjie Zhang, Trond Ulven, Xin Xie, Lena Björkman, Huamei Forsman
Formato: Artigo
Idioma:Inglês
Publicado em: Karger Publishers 2021-03-01
coleção:Journal of Innate Immunity
Assuntos:
neutrophils
g protein-coupled receptors
cross-talk
nicotine adenine dinucleotide phosphate oxidase
Acesso em linha:https://www.karger.com/Article/FullText/514887
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