Mandatory role of endoplasmic reticulum in preserving NADPH regeneration in starved MDA-MB-231 breast cancer cells

Cancer growth requires high amount of nicotinamide adenine dinucleotide phosphate (NADPH) to feed the anabolic reactions and preserve the redox balance. NADPH level is largely preserved by the oxidative arm of the pentose phosphate pathway (PPP). Here, we show that prolonged glucose deprivation of t...

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Bibliografische gegevens

Hoofdauteurs:	Sonia Carta, Vanessa Cossu, Francesca Vitale, Matteo Bauckneht, Maddalena Ghelardoni, Anna Maria Orengo, Serena Losacco, Daniela Gaglio, Silvia Bruno, Sabrina Chiesa, Silvia Ravera, Gianmario Sambuceti, Cecilia Marini
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2024-10-01
Reeks:	Heliyon
Onderwerpen:	Triple negative breast cancer Glucose metabolism NADPH G6PD H6PD Pentose phosphate pathway
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2405844024147494
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