Human cerebral organoids reveal PFOA-induced axonal injury as a conserved mechanism of neurodevelopmental disruption

Perfluorooctanoic acid (PFOA), a persistent environmental contaminant of growing public health concern, has been epidemiologically linked to neurodevelopmental deficits, yet its direct pathogenic mechanisms remain poorly defined. Our study addresses this critical gap by employing a unique cross-spec...

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Detalhes bibliográficos

Principais autores:	Wei-Ran Chen, Yun Huang, Wei Zhou, Jian Yang, Tai Ren, Lingli Zhang, Tailin Zhu, Xingyue Shan, Yatao Du, Guangdi Zhou, Yongjie Liu, Yunjun Sun, Qianlong Zhang, Wei-Guang Li, Yi Dong, Fei Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-04-01
coleção:	Environment International
Assuntos:	PFOA Social behavior Prenatal exposure Cerebral organoids NEFL
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0160412026001911
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