Protocol for generation and engineering of thyroid cell lineages using CRISPR-Cas9 editing to recapitulate thyroid cancer histotype progression

Summary: Thyroid carcinoma represents the first malignancy among the endocrine organs. Investigating the cellular hierarchy and the mechanisms underlying the initiation of thyroid carcinoma is crucial in thyroid cancer research. Here, we present a protocol for deriving thyroid cell lineage from huma...

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主要な著者:	Vincenzo Davide Pantina, Francesco Verona, Alice Turdo, Veronica Veschi, Chiara Modica, Melania Lo Iacono, Miriam Gaggianesi, Sebastiano Di Bella, Matilde Todaro, Simone Di Franco, Giorgio Stassi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2024-09-01
シリーズ:	STAR Protocols
主題:	Cell culture Cancer CRISPR Cell Differentiation
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2666166724004283
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