Comparative analysis of right ventricular metabolic reprogramming in pre-clinical rat models of severe pulmonary hypertension-induced right ventricular failure

BackgroundPulmonary hypertension (PH) leads to right ventricular (RV) hypertrophy and failure (RVF). The precise mechanisms of the metabolic basis of maladaptive PH-induced RVF (PH-RVF) are yet to be fully elucidated. Here we performed a comparative analysis of RV-metabolic reprogramming in MCT and...

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Detalhes bibliográficos

Principais autores:	Somanshu Banerjee, Jason Hong, Soban Umar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-09-01
coleção:	Frontiers in Cardiovascular Medicine
Assuntos:	pulmonary hypertension right ventricular failure targeted metabolomics monocrotaline Joint Pathway Analysis multi-omics
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.935423/full
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