Inhaled “Muco‐Trapping” Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections

Abstract Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in infants, the immunocompromised, and the elderly. RSV infects the airway epithelium via the apical membrane and almost exclusively sheds progeny virions back into the airway mucus (AM), making RSV difficult to ta...

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Detalhes bibliográficos

Principais autores:	Morgan D. McSweeney, Sarhad Alnajjar, Alison M. Schaefer, Zach Richardson, Whitney Wolf, Ian Stewart, Pun Sriboonyapirat, Justin McCallen, Ellen Farmer, Bernadette Nzati, Sam Lord, Brian Farrer, Thomas R. Moench, Priya A. Kumar, Harendra Arora, Raymond J. Pickles, Anthony J. Hickey, Mark Ackermann, Samuel K. Lai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-03-01
coleção:	Advanced Science
Assuntos:	mAb nebulization monoclonal antibody nebulization respiratory syncytial virus RSV
Acesso em linha:	https://doi.org/10.1002/advs.202306729
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