Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL

Population studies have found that a natural human apoA-I variant, apoA-I[K107del], is strongly associated with low HDL-C but normal plasma apoA-I levels. We aimed to reveal properties of this variant that contribute to its unusual phenotype associated with atherosclerosis. Our oil-drop tensiometry...

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Prif Awduron:	Irina N. Gorshkova, Nathan L. Meyers, Haya Herscovitz, Xiaohu Mei, David Atkinson
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2023-02-01
Cyfres:	Journal of Lipid Research
Pynciau:	Apolipoprotein A-I lipoproteins ABCA1 cholesterol/efflux natural/mutation HDL-C
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0022227522001523
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