SERINC5 Inhibits the Secretion of Complete and Genome-Free Hepatitis B Virions Through Interfering With the Glycosylation of the HBV Envelope

Serine incorporator 3 (SERINC3) and SERINC5 were recently identified as host intrinsic factors against human immunodeficiency virus (HIV)-1 and counteracted by HIV-1 Nef. However, whether they inhibit hepatitis B virus (HBV), which is a severe health problem worldwide, is unknown. Here, we demonstra...

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主要な著者:	Yue Liu, Hong Wang, Jun Zhang, Jing Yang, Lu Bai, Baisong Zheng, Tianhang Zheng, Yingchao Wang, Jianhua Li, Wenyan Zhang
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2020-04-01
シリーズ:	Frontiers in Microbiology
主題:	hepatitis B virus (HBV) serine incorporator 5 (SERINC5) secretion inhibitory mechanism glycosylation host–pathogen interaction
オンライン･アクセス:	https://www.frontiersin.org/article/10.3389/fmicb.2020.00697/full
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