PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability

Regulatory T (Treg) cells have been implicated in the induction of airway tolerance and amelioration of respiratory duct inflammation. Here the authors show, using PD-L2 deficient mice, that the immune suppression signal from PD-L2 is important for modulating Treg cell metabolism and function for pr...

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Detalhes bibliográficos

Principais autores:	Benjamin P. Hurrell, Doumet Georges Helou, Emily Howard, Jacob D. Painter, Pedram Shafiei-Jahani, Arlene H. Sharpe, Omid Akbari
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2022-08-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-022-32899-5
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