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Histological analysis of nucleus pulposus tissue from patients with lumbar disc herniation after condoliase administration

Abstract Background Condoliase is an enzyme used as a treatment for lumbar disc herniation (LDH). This enzyme degrades chondroitin sulfate (CS) in the nucleus pulposus of the intervertebral disc (IVD). However, there are cases in which symptoms do not improve, despite condoliase administration. This...

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Principais autores: Yuka Minamisawa, Taiichi Shirogane, Ippei Watanabe, Akira Dezawa
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley 2024-06-01
סדרה:JOR Spine
נושאים:
chemonucleolysis
chondroitin sulfate
condoliase
immunohistochemistry
lumbar disc herniation
גישה מקוונת:https://doi.org/10.1002/jsp2.1328
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