Somatic cell reprogramming from different origins and donors into iPSC, with four factors OSKM using viral Sendai vectors

Notocordal-like cells (NLCs) produced from hiPSCs is considered as a promising candidate for cell-based regenerative therapies to treat intervertebral disk degeneration (IVDD). However, OCT4, SOX2, KLF4, C-MYC (OSKM) reprogramming into iPSC was described to maintain (epi)genomic hallmarks of the ori...

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Hlavní autoři:	Romain Desprat, Mikael Magnano, Paul Bensadoun, Mathis Soubeyrand, Patrick Callier, Quentin Alle, Anaelle Bailly, Benjamin Gantenbein, Lisanne T. Laagland, Mariana Tryfonidou, Jerome Guicheux, Anne Camus, Ollivier Milhavet, Jean-Marc Lemaitre
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-08-01
Edice:	Stem Cell Research
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1873506125000868
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