Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells.

A peptidyl prolyl cis/trans isomerase, Pin1, regulates insulin signal transduction. Pin1 reduces responses to insulin stimulation by binding CRTC2 (CREB-regulated transcriptional co-activator 2) and PPARγ (peroxisome prolifereator- activated receptor γ), but conversely enhances insulin signaling by...

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Главные авторы:	Takafumi Uchida, Kengo Furumai, Tomokazu Fukuda, Hirotada Akiyama, Mika Takezawa, Tomoichiro Asano, Fumihiro Fujimori, Chiyoko Uchida
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2012-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC3296696?pdf=render
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