In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism

GAGs exhibit a high level of conformational and configurational diversity, which remains untapped in terms of the recognition and modulation of proteins. Although GAGs are suggested to bind to more than 800 biologically important proteins, very few therapeutics have been designed or discovered so fa...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Balaji Nagarajan, Nehru Viji Sankaranarayanan, Umesh R. Desai
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2022-01-01
Σειρά:	Biomolecules
Θέματα:	chondroitin sulfate conformational analysis glycosaminoglycans hydrogen bonding molecular dynamics potential energy surface
Διαθέσιμο Online:	https://www.mdpi.com/2218-273X/12/1/77
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