Inactivated Enterovirus 71 Vaccine Produced by 200-L Scale Serum-Free Microcarrier Bioreactor System Provides Cross-Protective Efficacy in Human SCARB2 Transgenic Mouse.

Epidemics and outbreaks caused by infections of several subgenotypes of EV71 and other serotypes of coxsackie A viruses have raised serious public health concerns in the Asia-Pacific region. These concerns highlight the urgent need to develop a scalable manufacturing platform for producing an effect...

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Autori principali:	Chia-Ying Wu, Yi-Wen Lin, Chia-Ho Kuo, Wan-Hsin Liu, Hsiu-Fen Tai, Chien-Hung Pan, Yung-Tsung Chen, Pei-Wen Hsiao, Chi-Hsien Chan, Ching-Chuan Chang, Chung-Cheng Liu, Yen-Hung Chow, Juine-Ruey Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2015-01-01
Serie:	PLoS ONE
Accesso online:	http://europepmc.org/articles/PMC4543551?pdf=render
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