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Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments

Purpose: RANKL expression in the tumor microenvironment has been identified as a biomarker of immune suppression, negating the effect of some cancer immunotherapies. Previously we had developed a radiotracer based on the FDA-approved RANKL-specific antibody denosumab, [<sup>89</sup>Zr]Zr-DFO-denosum...

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Váldodahkkit: Jonatan Dewulf, Ivanna Hrynchak, Sarah Geudens, Isabel Pintelon, Christel Vangestel, José Sereno, Peter A. van Dam, Antero J. Abrunhosa, Filipe Elvas, Tim Van den Wyngaert
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-04-01
Ráidu:Pharmaceutics
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Liŋkkat:https://www.mdpi.com/1999-4923/14/5/939
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