The impact of CSF1R inhibitor-mediated microglial depletion in rodent models of Alzheimer’s and Parkinson’s disease: a systematic review and meta-analysis

Microglia are central nervous system immune cells that support brain homeostasis but can adopt harmful roles in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), depending on the disease stage and progression. Thus, targeting microglia through depletion has em...

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Автори:	Ana Flavia F. Ferreira, Ana Caroline Santos-Silva, Beatriz Gangale Muratori, Luiz Roberto Britto
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2026-02-01
Серія:	Frontiers in Aging Neuroscience
Предмети:	CSF1-R inhibition microglial depletion microglial repopulation neurodegeneration neuroprotection
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fnagi.2026.1733682/full
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