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Nucleotide discrimination with DNA immobilized in the MspA nanopore.

Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing platform. An ionic current passing through a small pore would directly map the sequence of single stranded DNA (ssDNA) driven through the constriction. The pore protein, MspA, derived from Mycobacterium smegmatis, has...

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Bibliografische gegevens
Hoofdauteurs: Elizabeth A Manrao, Ian M Derrington, Mikhail Pavlenok, Michael Niederweis, Jens H Gundlach
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2011-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3186796?pdf=render
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