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eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.

While advancements in genome sequencing have identified millions of somatic mutations in cancer, their functional impact is poorly understood. We previously developed the expression-based variant impact phenotyping (eVIP) method to use gene expression data to characterize the function of gene varian...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alexis M Thornton, Lishan Fang, April Lo, Maria McSharry, David Haan, Casey O'Brien, Alice H Berger, Marios Giannakis, Angela N Brooks
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2021-07-01
Cyfres:PLoS Computational Biology
Mynediad Ar-lein:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009132&type=printable
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