RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease

Abstract RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death. Its downregulation in Parkinson’s and Huntington’s disease models ameliorates the pathological phenotypes. In the context of Alzheimer’s disease (AD), the coding gene for RTP...

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Detalhes bibliográficos

Principais autores:	Leticia Pérez-Sisqués, Anna Sancho-Balsells, Júlia Solana-Balaguer, Genís Campoy-Campos, Marcel Vives-Isern, Ferran Soler-Palazón, Marta Anglada-Huguet, Miguel-Ángel López-Toledano, Eva-Maria Mandelkow, Jordi Alberch, Albert Giralt, Cristina Malagelada
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2021-06-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-021-03899-y
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