Exploring Pharmacological Activities and Signaling of Morphinans Substituted in Position 6 as Potent Agonists Interacting with the μ Opioid Receptor

Background: Opioid analgesics are the most effective drugs for the treatment of moderate to severe pain. However, they also produce several adverse effects that can complicate pain management. The μ opioid (MOP) receptor, a G protein-coupled receptor, is recognized as the opioid receptor type which...

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Hlavní autoři:	Tanila Ben Haddou, Davide Malfacini, Girolamo Calo, Mario D Aceto, Louis S Harris, John R Traynor, Andrew Coop, Helmut Schmidhammer, Mariana Spetea
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SAGE Publishing 2014-07-01
Edice:	Molecular Pain
On-line přístup:	https://doi.org/10.1186/1744-8069-10-48
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