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Some pharmacogenetic aspects of the <i>ABCB1</i> gene in lopinavir / ritonavir concentration variability in children with HIV infection: A pilot study

Polymorphic variants of the multidrug resistance gene (ABCB1 or MDR1) are associated with changes in the absorption and transport of drugs in the body. One of the substrates of the ABCB1 transporter is an antiretroviral drug from the class of protease inhibitors, lopinavir.   The aim. To research th...

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Auteurs principaux: A. Yu. Sambyalova, T. A. Bairova, T. L. Manaenkova, A. V. Belskikh, E. V. Belyaeva, O. A. Ershova, D. V. Kumratov, A. I. Paramonov, Yu. K. Plotnikova, L. V. Kolomeets, L. V. Rychkova
Format: Artigo
Langue:Russo
Publié: Scientific Сentre for Family Health and Human Reproduction Problems 2022-12-01
Collection:Acta Biomedica Scientifica
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Accès en ligne:https://www.actabiomedica.ru/jour/article/view/3801
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