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Bioactivity of orange-spotted grouper (Epinephelus coioides) interleukin-6 in innate immunity: Inducing inflammation, antimicrobial peptides, and innate immune molecular gene expression as well as activating phagocytosis of leukocytes and increasing survival under Vibrio and NNV infection

Interleukin-6 (IL-6) is a multifunctional cytokine involved in innate and acquired immunity. In mammals, IL-6 can induce the secretion of acute-phase proteins (APPs) and antimicrobial peptides, activate macrophages and neutrophils, and regulate the expression of inflammatory cytokines in innate immu...

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Principais autores: Han-Tso Lin, Lih-Chiann Wang, Yun-Ru Chiang, Yi-Fan Fang, Fu-I. Lu, John Han-You Lin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-06-01
Serier:Aquaculture Reports
Fag:
Epinephelus coioides
Orange-spotted grouper
Interleukin-6
Innate immunity
Anti-microbial peptides
Immune cells
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352513422001399
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