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Molecular-oxygen-promoted Cu-catalyzed oxidative direct amidation of nonactivated carboxylic acids with azoles

A copper-catalyzed oxidative direct formation of amides from nonactivated carboxylic acids and azoles with dioxygen as an activating reagent is reported. The azole amides were produced in good to excellent yields with a broad substrate scope. The mechanistic studies reveal that oxygen plays an essen...

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Principais autores: Wen Ding, Shaoyu Mai, Qiuling Song
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015-11-01
coleção:Beilstein Journal of Organic Chemistry
Assuntos:
Acesso em linha:https://doi.org/10.3762/bjoc.11.233
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