An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats

Feline infectious peritonitis (FIP) is a fatal disease of cats that currently lacks licensed and affordable vaccines or antiviral therapeutics. The disease has a spectrum of clinical presentations including an effusive (“wet”) form and non-effusive (“dry”) form, both of which may be complicated by n...

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Hauptverfasser:	Sarah Cook, Luke Wittenburg, Victoria C. Yan, Jacob H. Theil, Diego Castillo, Krystle L. Reagan, Sonyia Williams, Cong-Dat Pham, Chun Li, Florian L. Muller, Brian G. Murphy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-11-01
Schriftenreihe:	Viruses
Schlagworte:	feline infectious peritonitis FIPV coronavirus antiviral pharmacokinetics combined anti-coronaviral therapy
Online-Zugang:	https://www.mdpi.com/1999-4915/14/11/2429
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