Influence of diabetes on the efficacy of DL-3-n-butylphthalide in post-stroke cognitive impairment: a 12-month prospective cohort study

ObjectiveDiabetic chronic hyperglycaemia amplifies oxidative stress, microvascular injury, and insulin-resistant neuroinflammation, counteracting the pro-angiogenic, mitochondrial-protective, and anti-apoptotic effects of DL-3-n-butylphthalide (NBP). It remains unknown whether glycaemic status modul...

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Auteurs principaux:	Yuting Lu, Lifeng Wang, Juan Hao, Jingjing Song, Chenxi Fan, Xianjia Ning, Jinghua Wang, Yan Li
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-11-01
Collection:	Frontiers in Aging Neuroscience
Sujets:	ischemic stroke cognitive impairment Dl-3-n-butylphthalide diabetes mellitus neuroprotection
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1649248/full
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