Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator

Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (INaP) and calcium-activated non-selective cation current (ICAN) are key biophysical factors that, respectively, generate inspiratory rhythm and burst pattern in the mammalian preBö...

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Prif Awduron:	Ryan S Phillips, Hidehiko Koizumi, Yaroslav I Molkov, Jonathan E Rubin, Jeffrey C Smith
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	eLife Sciences Publications Ltd 2022-07-01
Cyfres:	eLife
Pynciau:	respiratory rhythm generation pattern generation computational modeling preBӧtzinger complex
Mynediad Ar-lein:	https://elifesciences.org/articles/74762
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