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Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences

Coronavirus disease 2019 (COVID-19) has caused massive disruptions to society and the economy, and the transcriptional regulatory mechanisms behind the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are poorly understood. Herein, we determined the crystal structure of the SARS-CoV-2 nu...

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Principais autores: Mei Yang, Suhua He, Xiaoxue Chen, Zhaoxia Huang, Ziliang Zhou, Zhechong Zhou, Qiuyue Chen, Shoudeng Chen, Sisi Kang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-01-01
Serier:Frontiers in Chemistry
Fag:
COVID-19
coronavirus
SARS-CoV-2
nucleocapsid protein
C terminal domain
crystal structure
Online adgang:https://www.frontiersin.org/articles/10.3389/fchem.2020.624765/full
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