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A Structure-Based View on ABC-Transporter Linked to Multidrug Resistance

The discovery of the first ATP-binding cassette (ABC) transporter, whose overexpression in cancer cells is responsible for exporting anticancer drugs out of tumor cells, initiated enormous efforts to overcome tumor cell multidrug resistance (MDR) by inhibition of ABC-transporter. Because of its many...

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Détails bibliographiques
Auteurs principaux: Jiahui Huang, Gerhard F. Ecker
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2023-01-01
Collection:Molecules
Sujets:
Accès en ligne:https://www.mdpi.com/1420-3049/28/2/495
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